IDNutrition / Methylation+


Methylation+ is a groundbreaking blend of essential vitamins that play a vital role in the body's methylation process. This unique formula also contains carrier ingredients that optimize absorption and promote the elimination of dead, damaged, and toxic cells.

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Methylation+ is a cutting-edge supplement that harnesses the power of methylated forms of vitamins B9 (Folate) and B12, along with Trimethylglicine (Betaine Anhydrous), to enhance the body's uptake and metabolism of these crucial B vitamins. Moreover, the formula is enriched with a patented form of PhosphalidylSerine, which facilitates the methylation process by identifying and eliminating dead, damaged, and toxic cells. This unique blend of vital nutrients is particularly essential for individuals with MTHFR genetic markers, as it ensures greater bioactivity, maximizes absorption, and optimizes cellular uptake.


5-MTHF ((6S)-5-Methyltetrahydrofolic Acid, Glucosamine Salt), Vitamin B12 (as Methylcobalamin), Betaine Anhydrous (Trimethylglicine), PhophalidylSerine (SerinAid®), Vitamin C, Vitamin B2, and Vitamin B6

Benefits of Methylation+

May help support a healthy cardiovascular system and blood pressure.

Powerful combination of antioxidants that may help battle free radicals and the ill effects of oxidative stress.

Carefully chosen mineral profile that may help support the body's natural energy system and sleep-wake cycle.

Protects your cells from free radical damage.

This supplement is essential for maintaining healthy levels of homocysteine, an amino acid that can be harmful in excessive amounts. Moreover, it plays a crucial role in the formation of both red and white blood cells. Additionally, it supports the production of healthy white blood cells and activity, which are vital to a properly functioning immune system and response.


This supplement is beneficial in reducing levels of homocysteine, an amino acid that has been associated with a higher risk of fractures. Research has demonstrated that folate intake not only lowers homocysteine but also has additional positive effects on bone-mass density. On the other hand, folate deficiencies can lead to weakened bones, which can complicate the treatment of fractures and result in further complications related to fragile bone structure.


In recent years, a substantial amount of research has demonstrated that elevated levels of homocysteine in the bloodstream are an independent risk factor for heart disease. This increase can result in the formation of hazardous blood clots and hardening of the arteries. As such, supplementing with easily digestible forms of folate and B12 is a straightforward strategy to reduce homocysteine levels and mitigate the risk of these cardiovascular complications.


The foundation of our overall well-being lies in the health of our cells. The methylation process plays a fundamental role in the production and maintenance of every cell in the body. This process is especially crucial for children and athletes. Methylation+ is a supplement that contains essential nutrients required by the body to produce DNA and RNA, the genetic materials that regulate cellular function. Moreover, these nutrients help to prevent mutations in our DNA, which can lead to the development of illnesses and diseases.


Folate and B12 are renowned for their effectiveness in lowering homocysteine levels in the blood. However, recent studies have also suggested that these vitamins can promote relaxation of blood vessels, improve circulatory health and flow, and reduce the risk of high blood pressure. Furthermore, folate and B12 are essential for the formation and growth of red blood cells, which supply critical oxygen to tissues and muscles throughout the body.

Energy & Mood

Individuals experiencing chronic fatigue or weakness, brain fog, and unexplained mood swings may find support from the ingredients found in Methylation+. This supplement contains highly absorbable forms of Folate and B12 that support the conversion of food into energy, promote healthy brain function, and have been shown to positively impact mood.

What's your health goal?

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